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Medicinal Chemistry Degree Requirements

  • Ph.D. in Medicinal Chemistry

  • M.S. in Medicinal Chemistry

 

 

Ph.D. Program in Medicinal Chemistry

Degree requirements:

  • 50% or higher for the Graduate Record Examination (GRE) Subject Exam in Biochemistry, Cell and Molecular Biology (BCMB).

    All students must attain a 50% or higher on the BCMB GRE by July 1 of their first year in residence to continue in the program. Students scoring less than 33% on the BCMB GRE are not admitted. Students scoring from 33% to 49% on the GRE BCMB will be required to take BMED 600 (Advanced Cellular Biochemistry; 3 cr.) or an equivalent course in year one of the program and must receive a grade of ‘B’ or better as well as retake the GRE Subject Exam with a passing grade greater than or equal to 50%. Students may retake the BCMB test at any time in year one.

    Students attaining greater than or equal to 50% prior to program entry achieve a passing level and are excluded from retaking the BCMB GRE exam and taking BMED 600 (or equivalent course);

     
  • Greater than or equal to 70% or higher for the American Chemical Society (ACS) exam in organic chemistry for undergraduates.

    All students must demonstrate proficiency in Organic Chemistry. All students will take this placement exam at least one week before the first semester. A score of greater than or equal to 70% is required. Students that do not meet this level of proficiency must meet one of the following three criteria to continue in the program:
    1. take as one of their electives, BMED 625 ‘Drug Synthesis’ and achieve a grade ‘B’ or better,
    2. retake the ACS Standardized exam in Organic Chemistry by July 1 of their first year in the program and pass at 70% or better, or
    3. pass an oral comprehensive exam in organic chemistry administered by no less than two of the Medicinal Chemistry faculty.
  • Successful completion of at least 60 graduate semester credits.
  • Completion of core curriculum with a minimum GPA of 3.0. Students receiving grades of "C" or lower in two or more core classes will not be permitted to continue in the program.
  • Successful completion of the lab component in BMED 621 and BMED 622 with combined lab report and qualitative grades of "B" or better.
  • Pass 4 of 7 written cumulative exams by the end of the 4th semester in residence.
  • Successful defense of a written/oral out of field qualifying exam.
  • Three seminar presentations and three written research reports in BMED 627.
  • One department research presentation in the semester following completion of the cumulative exam requirement.
  • Adequate progress in research as defined by grades in research courses, research reports, activity at professional meetings, and patents/publications. At least one peer-reviewed manuscript or provisional patent must be submitted prior to the Ph.D. defense.
  • Completion and defense of the Ph.D. dissertation.

 

Course of Study:

The Medicinal Chemistry Ph.D. degree typically takes four and a half to five years of research training and education in which students concentrate on course work in the first two years.   Core classes include lecture style courses (e.g., BMED 615, BMED 623), lecture and laboratory learning (e.g, BMED 621, 622), seminars (attend and present), workshops, and professional development (e.g., BMED 627).  Professional Development (BMED 627; taken thrice) will educate students in oral/written scientific presentations, scientific software, teaching methods and models, modern research methods, scientific ethics, intellectual property & patents, entrepreneurial endeavors, small business opportunities (SBIR), grant writing, collaborations, safety/chemical handling/hazardous disposal, chemical hygiene, job preparation, and animal and human subjects (incl. HEPA). 

Course Requirements:

The following core courses are required of all students in the Ph.D. program:

BMED 615

Molecular Pharmacology

3 cr.

BMED 621

Drug Design, Development and Discovery + Lab

4 cr.

BMED 622

Drug Pharmacodynamics - Drug Receptor Interactions + Lab

4 cr.

BMED 623

Drug Diversity and Target - Oriented Synthesis

3 cr.

BMED 627*

Professional Development - Medicinal Chemistry

1 cr.

*    Course will be taken for three semesters (content varies) for a total of 3 credits.

 

Students will take at least three of the following courses, according to research interest:

BIOC 581

Physical Biochemistry

3 cr.

BIOC 582

Peptides and Proteins

3 cr.

BIOC 588

Biomolecular Structure and Dynamics

4 cr.

BMED 600

Advanced Cellular Biochemistry

3 cr.

BMED 624

Special Topics in Medicinal Chemistry

3 cr.

BMED 625

Drug Synthesis

3 cr.

BMED 641

Toxicology I – Principles of Toxicology

4 cr.

BMED 642

Toxicology II – Toxic Agents

4 cr.

BMED 661

Neuroscience I

4 cr.

BMED 662

Neuroscience II

4 cr.

CHEM 562

Organic Structure and Mechanism

3 cr.

CHEM 563

Organic Synthesis

3 cr.

COMP 458

Introduction to Bioinformatics

3 cr.



The following are examples of additional elective courses available to meet student interests:

BMED 610

Neuropharmacology

3 cr.

BMED 630

Pharmacogenetics

3 cr.

BMED 643

Cellular and Molecular Toxicology

4 cr.

BMED 646

Neurotoxicology

2 cr.

CHEM 581

Chemical Biology

3 cr.

 

Research, Thesis, and Dissertation credits

BMED 697*

Research (PhD)

1-9 cr.

BMED 699*

Dissertation (PhD)

1-9 cr.

* Up to 30 credits total

 

Course descriptions can be found in the online University of Montana Catalog at http://www.umt.edu/catalog/pharmacy.htm.

 

 

M.S. Program in Medicinal Chemistry

 

Degree requirements:

  • 50% or higher for the Graduate Record Examination (GRE) Subject Exam in Biochemistry, Cell and Molecular Biology (BCMB).

    All students must attain a 50% or higher on the BCMB GRE by July 1 of their first year in residence to continue in the program. Students scoring less than 33% on the BCMB GRE are not admitted. Students scoring from 33% to 49% on the GRE BCMB will be required to take BMED 600 (Advanced Cellular Biochemistry; 3 cr.) or an equivalent biochemistry course in year 1 of the program, and must receive a grade of ‘B’ or better as well as retake the GRE Subject Exam with a passing grade greater than or equal to 50%. Students may retake the BCMB test at any time in year one.

    Students attaining greater than or equal to 50% prior to program entry achieve a passing level and are excluded from retaking the BCMB GRE exam and taking BMED 600 (or equivalent course);

     
  • Greater than or equal to 70% for the American Chemical Society (ACS) exam in organic chemistry for undergraduates.

    All students must demonstrate proficiency in Organic Chemistry. All students will take this placement exam at least one week before the start of the first semester. A score of 70% or greater is required. Students that do not meet this level of proficiency must meet one of the following three criteria to continue in the program:
    1. take as one of their electives, BMED 625 ‘Drug Synthesis’ with a grade of ‘B’ or better,
    2. retake the ACS Standardized exam in Organic Chemistry by July 1 of their first year in the program and pass at 70% or better, or
    3. pass an oral comprehensive exam in organic chemistry administered by no less than two of the Medicinal Chemistry faculty.
  • Successful completion of at least 30 graduate semester credits.
  • Completion of core curriculum with a minimum GPA of 3.0.
  • Successful completion of the lab component in BMED 621 and BMED 622 with combined lab report and qualitative grades of ‘C‘ or better.
  • Three seminar presentations and three written research reports in BMED 627.   
  • One department research presentation in the semester following completion of the cumulative exam requirement.
  • Adequate progress in research as defined by grades in research courses and patents/publications. At least one peer-reviewed manuscript or provisional patent must be submitted prior to the M.S. defense.
  • Completion and defense of the M.S. thesis.

 

Course of Study:

M.S. degree training typically consists of one year of course work and one to two additional years of research leading to the completion and defense of the thesis. Core classes include lecture style courses (e.g., BMED 615, BMED 623), lecture and laboratory learning (e.g., BMED 621, 622), seminars (attend and present), workshops, and professional development (e.g., BMED 627).  Professional Development (BMED 627; taken thrice) will educate students in oral/written scientific presentations, scientific software, teaching methods and models, modern research methods, scientific ethics, intellectual property & patents, entrepreneurial endeavors, small business opportunities (SBIR), grant writing, collaborations, safety/chemical handling/hazardous disposal, chemical hygiene, job preparation, and animal and human subjects (incl. HEPA). 

Course Requirements:

The following core courses are required of all students in the M.S. program:

BMED 615

Molecular Pharmacology

3 cr.

BMED 621

Drug Design, Development and Discovery + Lab

4 cr.

BMED 622

Drug Pharmacodynamics - Drug Receptor Interactions + Lab

4 cr.

BMED 623

Drug Diversity and Target - Oriented Synthesis

3 cr.

BMED 627*

Professional Development - Medicinal Chemistry

1 cr.

*    Course will be taken for three semesters (content varies) for a total of 3 credits.

 

Students will take at least two of the following courses, according to research interest:

BIOC 581

Physical Biochemistry

3 cr.

BIOC 582

Peptides and Proteins

3 cr.

BIOC 588

Biomolecular Structure and Dynamics

4 cr.

BMED 600

Advanced Cellular Biochemistry

3 cr.

BMED 624

Special Topics in Medicinal Chemistry

3 cr.

BMED 625

Drug Synthesis

3 cr.

BMED 641

Toxicology I – Principles of Toxicology

4 cr.

BMED 642

Toxicology II – Toxic Agents

4 cr.

BMED 661

Neuroscience I

4 cr.

BMED 662

Neuroscience II

4 cr.

CHEM 562

Organic Structure and Mechanism

3 cr.

CHEM 563

Organic Synthesis

3 cr.

COMP 458

Introduction to Bioinformatics

3 cr.



The following are examples of additional elective courses available to meet student interests:

BMED 610

Neuropharmacology

3 cr.

BMED 630

Pharmacogenetics

3 cr.

BMED 643

Cellular and Molecular Toxicology

4 cr.

BMED 646

Neurotoxicology

2 cr.

CHEM 581

Chemical Biology

3 cr.

 

Research, Thesis, and Dissertation credits:

BMED 597*

Research (MS)

1-9 cr.

BMED 599*

Thesis (MS)

1-9 cr.

* Up to 10 credits total

 

Course description can be found in the online University of Montana Catalog at http://www.umt.edu/catalog/pharmacy.htm

The University of Montana-Missoula
The Department of Biomedical & Pharmaceutical Sciences
32 Campus Drive, Skaggs 395
Missoula, MT 59812-1552
Phone 406.243.4767 Fax: 406.243.5228
Email: biomed@umontana.edu

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